Pexidartinib [1029044-16-3]
HY-16749
Overview
- SupplierMedChem Express
- Product NamePexidartinib [1029044-16-3]
- Delivery Days Customer10
- CAS Number1029044-16-3
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC20H15ClF3N5
- Molecular Weight417.81
- Scientific DescriptionPexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.
- SMILESFC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200