Nirogacestat [1290543-63-3]
HY-15185
CAS Number1290543-63-3
Product group Chemicals
Estimated Purity97.5%
Molecular Weight489.64
Overview
- SupplierMedChem Express
- Product NameNirogacestat [1290543-63-3]
- Delivery Days Customer10
- CAS Number1290543-63-3
- CertificationResearch Use Only
- Estimated Purity97.5%
- Molecular FormulaC27H41F2N5O
- Molecular Weight489.64
- Scientific DescriptionNirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective gamma-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers.
- SMILESFC1=C2C(CC[C@H](N[C@@H](CCC)C(NC3=CN(C(C)(C)CNCC(C)(C)C)C=N3)=O)C2)=CC(F)=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200