PF-3845 [1196109-52-0]

MedChem Express

PF-3845 [1196109-52-0]

10

1196109-52-0

Research Use Only

99.8%

C24H23F3N4O2

456.46

PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH), with a Ki of 0.23 microM. PF-3845 is a covalent inhibitor that carbamylates FAAHs serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition.

O=C(N1CCC(CC2=CC=CC(OC3=NC=C(C=C3)C(F)(F)F)=C2)CC1)NC4=CN=CC=C4

2°C to 8°C,-20°C,-80°C

12352200