PF-543 Citrate [1415562-83-2]
HY-15425A
CAS Number1415562-83-2
Product group Chemicals
Estimated Purity98.35%
Molecular Weight657.73
Overview
- SupplierMedChem Express
- Product NamePF-543 Citrate [1415562-83-2]
- Delivery Days Customer10
- CAS Number1415562-83-2
- CertificationResearch Use Only
- Estimated Purity98.35%
- Molecular FormulaC33H39NO11S
- Molecular Weight657.73
- Scientific DescriptionPF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy.
- SMILESOC(C(O)=O)(CC(O)=O)CC(O)=O.O=S(C1=CC=CC=C1)(CC2=CC(C)=CC(OCC3=CC=C(CN4[C@@H](CO)CCC4)C=C3)=C2)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200