Rapamycin [53123-88-9]
HY-10219
Overview
- SupplierMedChem Express
- Product NameRapamycin [53123-88-9]
- Delivery Days Customer10
- CAS Number53123-88-9
- Estimated Purity96.35%
- Molecular FormulaC51H79NO13
- Molecular Weight914.17
- Scientific DescriptionRapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
- SMILESO=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200