Remodelin hydrobromide [1622921-15-6]

MedChem Express

Remodelin hydrobromide [1622921-15-6]

10

1622921-15-6

Research Use Only

99.16%

C15H15BrN4S

363.28

Remodelin, a specific inhibitor of N-acetyltransferase NAT10, can ameliorate Hutchinson-Gilford Progeria Syndrom (HGPS) cellular phenotypes. Remodelin acts in a progerin- and FTI-independent pathway, by targeting and inhibiting NAT10. NAT10 is a protein with histone acetylation activity and primarily identified to be involved in regulation of telomerase activity.

N#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br

2°C to 8°C,-20°C,-80°C

12352200