Rigosertib sodium [592542-60-4]
HY-12037
CAS Number592542-60-4
Product group Chemicals
Estimated Purity95.91%
Molecular Weight473.47
Overview
- SupplierMedChem Express
- Product NameRigosertib sodium [592542-60-4]
- Delivery Days Customer10
- CAS Number592542-60-4
- CertificationResearch Use Only
- Estimated Purity95.91%
- Molecular FormulaC21H24NNaO8S
- Molecular Weight473.47
- Scientific DescriptionRigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.
- SMILESCOC1=CC=C(C=C1NCC(O[Na])=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200