Sorafenib Tosylate [475207-59-1]
HY-10201A
Overview
- SupplierMedChem Express
- Product NameSorafenib Tosylate [475207-59-1]
- Delivery Days Customer10
- CAS Number475207-59-1
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC28H24ClF3N4O6S
- Molecular Weight637.03
- Scientific DescriptionSorafenib Tosylate (Bay 43-9006 Tosylate) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. SorafenibTosylate is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRbeta, FLT3 and c-Kit, respectively. Sorafenib Tosylate induces autophagy and apoptosis. Sorafenib Tosylate has anti-tumor activity. Sorafenib Tosylate is a ferroptosis activator.
- SMILESO=S(C1=CC=C(C=C1)C)(O)=O.O=C(NC2=CC=C(C(C(F)(F)F)=C2)Cl)NC3=CC=C(OC4=CC(C(NC)=O)=NC=C4)C=C3
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200