Temozolomide (CCRG 81045) [85622-93-1]
S1237
Overview
- SupplierSelleck Chemicals
- Product NameTemozolomide (CCRG 81045) [85622-93-1]
- Delivery Days Customer9
- CAS Number85622-93-1
- CertificationResearch Use Only
- Scientific DescriptionTemozolomide (CCRG81045, NSC 362856, TMZ) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.
- UNSPSC12352200