Tofogliflozin (hydrate) [1201913-82-7]
HY-13413
CAS Number1201913-82-7
Product group Chemicals
Estimated Purity98.27%
Molecular Weight404.45
Overview
- SupplierMedChem Express
- Product NameTofogliflozin (hydrate) [1201913-82-7]
- Delivery Days Customer10
- CAS Number1201913-82-7
- CertificationResearch Use Only
- Estimated Purity98.27%
- Molecular FormulaC22H28O7
- Molecular Weight404.45
- Scientific DescriptionTofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.
- SMILESO[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200