Tofogliflozin (hydrate) [1201913-82-7]

MedChem Express

Tofogliflozin (hydrate) [1201913-82-7]

10

1201913-82-7

Research Use Only

98.27%

C22H28O7

404.45

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.

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2°C to 8°C,-20°C,-80°C

12352200