Y-320 [288250-47-5]
HY-15898
CAS Number288250-47-5
Product group Chemicals
Estimated Purity99.74%
Molecular Weight505.01
Overview
- SupplierMedChem Express
- Product NameY-320 [288250-47-5]
- Delivery Days Customer10
- CAS Number288250-47-5
- CertificationResearch Use Only
- Estimated Purity99.74%
- Molecular FormulaC27H29ClN6O2
- Molecular Weight505.01
- Scientific DescriptionY-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug resistance (MDR) tumors by inducing G2/M phase arrest and apoptosis. Y-320 can be used for research of rheumatoid arthritis (RA) and cancer.
- SMILESO=C(C1=C(C)N(C2=CC=C(Cl)C=C2)N=C1)NC3=CC=C(N4CCC(N5CCOCC5)CC4)C(C#N)=C3
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200