Zoledronic acid (ZOL 446) [118072-93-8]

Selleck Chemicals

Zoledronic acid (ZOL 446) [118072-93-8]

9

118072-93-8

Research Use Only

Zoledronic acid (ZOL 446, ZA, Zoledronate, CGP-4244, GP42446A, Zometa, Zomera, Aclasta, Reclast), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.

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