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Chemical Structure
Chemical Structure
Chemical Structure

Procyanidin A2 [41743-41-3]

Research Use Only
AG-CN2-0486
AdipoGen Life Sciences
CAS Number41743-41-3
Product group Chemicals
Estimated Purity>95% (NMR)
Molecular Weight576.5
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Procyanidin A2 [41743-41-3]
  • Delivery Days Customer
    10
  • CAS Number
    41743-41-3
  • Certification
    Research Use Only
  • Estimated Purity
    >95% (NMR)
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C30H24O12
  • Molecular Weight
    576.5
  • Scientific Description
    A-Type proanthocyanidine. Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor. Potent low-density lipoprotein (LDL) oxidation inhibitor. Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through its antioxidant properties. Antibacterial agent. Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV). Glycosyltransferase B (GTFB) inhibitor. - Chemical. CAS: 41743-41-3. Formula: C30H24O12. MW: 576.5. Isolated from grape seeds (Vitis vinifera L). A-Type proanthocyanidine. Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor. Potent low-density lipoprotein (LDL) oxidation inhibitor. Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through its antioxidant properties. Antibacterial agent. Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV). Glycosyltransferase B (GTFB) inhibitor.
  • SMILES
    OC1=CC(O)=C([C@H](C2=C(O[C@H](C3=CC(O)=C(O)C=C3)[C@H](O)C4)C4=C(O)C=C2O5)[C@@H](O)[C@@]5(C6=CC(O)=C(O)C=C6)O7)C7=C1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity: G.K. Jayaprakasha, et al.; J. Agric. Food Chem. 54, 1672 (2006)
  • Influence of cranberry phenolics on glucan synthesis by glucosyltransferases and Streptococcus mutans acidogenicity: S. Gregoire, et al.; J. Appl. Microbiol. 103, 1960 (2007)
  • Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo: H. Koo, et al.; Caries Res. 44, 116 (2010)
  • Doubly linked, A-type proanthocyanidin trimer and other constituents of Ixora coccinea leaves and their antioxidant and antibacterial properties: T.O. Idowu, et al.; Phytochemistry 71, 2092 (2010)
  • Inhibition of viral RNA synthesis in canine distemper virus infection by proanthocyanidin A2: L. Gallina, et al.; Antiviral Res. 92, 447 (2011)
  • Flavonoids from Lindera glauca blume as low-density lipoprotein oxidation inhibitors: G.W. Huh, et al.; Nat. Prod. Res. 28, 831 (2014)
  • Procyanidins from the stem wood of Machilus japonica and their inhibitory effect on LDL oxidation: H.J. Park, et al.; Arch. Pharm. Res. 37, 1403 (2014)
  • Chemical composition, antioxidant and antinociceptive properties of Litchi chinensis leaves: R.C. Castellain, et al.; J. Pharm. Pharmacol. 66, 1796 (2014)
  • Preventive effects of procyanidin A2 on glucose homeostasis, pancreatic and duodenal homebox 1, and glucose transporter 2 gene expression disturbance induced by bisphenol A in male mice: A. Ahangarpour, et al.; J. Physiol. Pharmacol. 67, 243 (2016)