AL 8697 [1057394-06-5]
HY-108645
Overview
- SupplierMedChem Express
- Product NameAL 8697 [1057394-06-5]
- Delivery Days Customer10
- CAS Number1057394-06-5
- Estimated Purity0.99
- Molecular FormulaC21H21F3N4O
- Molecular Weight402.41
- Scientific DescriptionAL 8697 is a specific and orally active p38alpha MAPK inhibitor with an IC50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38alpha compared to p38beta (IC50=82 nM), and 300-fold selectivity for p38alpha over a panel of 91 kinases. Anti-inflammatory activity.
- SMILESO=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200