GN44028 [1421448-26-1]
HY-110266
Overview
- SupplierMedChem Express
- Product NameGN44028 [1421448-26-1]
- Delivery Days Customer10
- CAS Number1421448-26-1
- CertificationResearch Use Only
- Estimated Purity0.99
- Molecular FormulaC18H15N3O2
- Molecular Weight305.33
- Scientific DescriptionGN44028 is a potent and orally active hypoxia inducible factor (HIF)-1alpha inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1alpha transcriptional activity without suppressing HIF-1alpha mRNA expression, HIF-1alpha protein accumulation, or HIF-1alpha/HIF-1beta heterodimerization. GN44028 can be used in the research of cancers.
- SMILESC1(NC2=CC=C(OCCO3)C3=C2)=NNC4=C1CC5=CC=CC=C45
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200