AZ1495 [2196204-23-4]

MedChem Express

AZ1495 [2196204-23-4]

10

2196204-23-4

Research Use Only

98%

C21H31N5O2

385.5

AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 microM and 0.023 microM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 microM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL).

C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4

2°C to 8°C,-20°C,-80°C

12352200