CD137 (human):Fc (human) (rec.)

Catalog number: AG-40B-0060-C050
Brand: AdipoGen Life Sciences
Packing: 50 ug
Other sizes: 3 x 50 ug
Price: € 250.00
Expected delivery time: 7 days
Quantity:

Product specifications for - CD137 (human):Fc (human) (rec.)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Species: Human
Target: TNFRSF9
Target description: TNF receptor superfamily member 9
Source: 293 Cells
Properties: 
Purity: >95% (SDS-PAGE)
Molecular weight: ~50kDa (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 1 mg/ml
Form supplied: Lyophilized. Contains PBS.
Storage instructions: -20-¦C
Scientific information: 
Scientific info: CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice. - Protein. The cysteine-rich region of human CD137 (aa 1-186) is fused to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human CD137L (4-1BBL). Purity: >95% (SDS-PAGE). CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
Gene ID: 3604
Swiss prot ID: Q07011
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: 4-1BB; 4-1BB ligand receptor; CD137; CD137 antigen; CDw137; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; T cell antigen ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA; tumor necrosis factor receptor superfamily member 9