CD278 [ICOS] (human)-muIg Fusion Protein (preservative free)

Catalog number: ANC-517-820
Brand: Ancell Corporation
Packing: 25 ug
Price: € 421.00
Expected delivery time: 7 days
Quantity:

Product specifications for - CD278 [ICOS] (human)-muIg Fusion Protein (preservative free)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Storage instructions: 2-¦C to 8-¦C
Scientific information: 
Scientific info: Protein. Liquid. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement. - The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.
Safety information: 
Hazard information: Non-hazardous
Additional information: 
Synonyms: ANC-517-820; Ancell Corporation