CD278 [ICOS] (human)-muIg Fusion Protein (preservative free)

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Product specifications for - CD278 [ICOS] (human)-muIg Fusion Protein (preservative free)

Overview:
Product group:	Proteins / Signaling Molecule
Category:	Proteins

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352202
Form supplied:	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Storage instructions:	2-¦C to 8-¦C

Scientific information:
Scientific info:	Protein. Liquid. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement. - The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.

Scientific information:

Scientific info:

Protein. Liquid. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement. - The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.

Safety information:
Hazard information:	Non-hazardous

Additional information:
Synonyms:	ANC-517-820; Ancell Corporation

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Product specifications for - CD278 [ICOS] (human)-muIg Fusion Protein (preservative free)