Human IL-9 protein

Biorbyt

Human IL-9 protein

16

HPLC, SDS-PAGE

Research Use Only

>95%

Interleukin-9 (IL-9) is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells. IL-9 wasoriginally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I (HTLVI)transformed T cell line. It functions through the IL-9 receptor, which activates different signal transducer and activator (STAT)proteins and thus connects this cytokine to various biological processes. IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells. Human IL-9 has approximately 56 % amino acid sequence identity with murine IL-9. The geneencoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthmademonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness

E.coli

2°C to 8°C,-20°C

12352202