Human IL-2 R beta protein

Biorbyt

Human IL-2 R beta protein

16

SDS-PAGE

Research Use Only

>95%

Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - alpha (CD25), beta (CD122) and gamma (CD132) - non-covalently associating. The alpha and beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the gamma-chain, along with the beta subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

-20°C

12352202