GTX68185-pro Image
Human RGS14 protein
GTX68185-PRO
Overview
- SupplierGeneTex
- Product NameHuman RGS14 protein
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration0.5 mg/ml
- Protein IDO43566
- Protein NameRegulator of G-protein signaling 14
- Scientific DescriptionThis gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202