Ultra-Clean DNA-Depleted Plasma for Oncology From ZeptoMetrix

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Utilizing ZeptoMetrix oncology controls and reagents helps to ensure consistent, accurate results and provides additional confidence in the development, validation, and implementation of molecular assays (NGS and PCR).

Benefits of DNA-Depleted Plasma for Oncology

Ideal for developers building high-sensitivity assays, our DNA-depleted plasma greatly reduces background – enabling you to build your own controls, save valuable time, and ensure exceptional assay performance.

ZeptoMetrix’ Human DNA-Depleted Plasma offers unique advantages:

• Proprietary DNA depletion process achieves DNA levels less than 4 pg/mL
• The depletion process decreases background DNA noise in plasma while keeping everything else consistent
• Using a patient-like matrix for quality control and assay valuation can result in a more accurate assay

Why Choose DNA-Depleted Plasma Over Buffer?

With our DNA-depleted plasma (DNA-free plasma) as a matrix, you can produce reference materials specific to your time-sensitive needs while retaining the natural components of the sample.

Advantages of DNA-depleted plasma Over Buffer or Synthetic Plasma

• Plasma matrix is a better representation of a real patient sample because the natural interfering proteins are retained.
• Risk of underestimation of assay Limit of Detection (LOD) when buffer or synthetic plasma were used as sample matrix
• The higher imprecision in both untreated patient plasma and DNA-depleted plasms is associated with higher, more accurate, Limit of Blank (LOB) and LOD for AF% determination.

Compared to buffer or synthetic plasma, using the human DNA-depleted plasma matrix provides a better representation of the real patient sample because the natural interfering proteins are retained.

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ZeptoMetrix’s Commitment to Oncology Research

ZeptoMetrix offers an extensive range of oncology quality controls and reagents that are trusted by assay developers around the world. Our controls eliminate background DNA noise while preserving the natural components of the sample. Build controls tailored to your high-positive samples and meet time-sensitive research demands.