Antibodies
Bio-Connect offers one of the most comprehensive portfolios of antibodies worldwide.
Host Cell DNA detection | Viral clearance | MS | Host Cell Protein (HCP) | ELISA | Biotherapeutics | Antibodies | WB | Immunoassay Reagents
Cygnus Technologies, part of Maravai LifeSciences, is the biopharmaceutical industry’s partner in host cell protein (HCP) and other process-related impurity detection and analytics as well as in innovative viral clearance solutions. Cygnus helps companies developing therapeutic proteins, vaccines, antibodies, plasma derivatives and gene therapies to ensure the safety of biotherapeutics prior to human trials, regulatory approval and commercial release.
Reduction of bioprocess impurities to the lowest levels practical requires sensitive and robust analytical methods. Cygnus offers a full menu of ELISA kits and orthogonal testing services for all current host cell expression systems and purification process leachates, such as Protein A.
Bio-Connect supplies all their products in the Benelux. If you have any questions, please contact the helpdesk.
DNA / RNA / Vectors
Chemicals
Assays
Assays
Assays
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Assays
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Quantification of Six HCP Lipases from CHO-Derived Biotherapeutics
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Antibody Affinity Extraction (AAE)
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Case Study: Antibody Coverage Analysis of E. coli HCPs in the BL21(DE3) strain by AAE-MS™
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Case Study: Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS™
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Cygnus Technologies specializes in the detection and analysis of host cell proteins (HCPs) and other bioprocess impurities and offers custom services to support process-specific impurity control strategies. Their custom antibody and assay development programs enable the generation of polyclonal antibodies and ELISA methods tailored to a specific expression system and manufacturing process. These programs are complemented by orthogonal analytical approaches such as Antibody Affinity Extraction (AAE), 2D-PAGE, and mass spectrometry to assess antibody coverage and support assay characterization.
Cygnus also provides comprehensive assay qualification and characterization services aligned with FDA and ICH expectations. These include studies such as dilution linearity, spike recovery, and impurity coverage analysis to demonstrate assay performance.
Through Bio-Connect, customers can access Cygnus Technologies’ custom antibody and impurity assay development services with scientific support. Our team works with you and Cygnus to translate process and regulatory requirements into clear assay specifications and coordinate the development of custom HCP and impurity assays tailored to your bioprocess.
We gladly support you by keeping you updated on our latest products and developments
