If you’re looking to streamline SNP detection with accuracy, flexibility, and reliability, Solis BioDyne’s new SolisAcura™ product family delivers exactly that.
Whether you prefer an optimized master mix or the freedom of a stand-alone polymerase kit, and whether your assays are cassette-based or probe-based, this product line offers powerful tools for every workflow.
SolisAcura™ products are designed for exceptional mismatch discrimination, high inhibitor tolerance, and increased fidelity and yield. SolisAcura™ is chemically modified to support robust performance across human, animal, and plant DNA applications. And thanks to Solis BioDyne’s proprietary stability TAG technology, the products are also exceptionally stable.
At the core of the product line is the novel HOT SolisAcura™ Exo(–) DNA Polymerase, engineered for superior mismatch recognition. Unlike standard Taq polymerase, this enzyme can detect misaligned nucleotides and halt extension from mismatched primers with unmatched accuracy.
This capability makes HOT SolisAcura™ Exo(–) DNA Polymerase ideal for a wide range of SNP detection assays, and you can choose between a stand-alone enzyme or a selection of optimized master mixes to suit your experimental needs.
The HOT SolisAcura™ Cassette-Based Genotyping Mix (with ROX reference dye) enables precise bi-allelic discrimination using a universal reverse primer paired with two allele-specific forward primers. Each primer includes a unique tail sequence that corresponds to one of two universal FRET cassettes, creating a flexible and efficient genotyping workflow.
This mix excels in applications like:
Plus, thanks to its outstanding inhibitor tolerance, you can use crude plant samples, like corn, soy, tomato, and more, without extensive purification.
Bonus: The mix is compatible with similar cassette-based assays, so you can continue using your existing primers.
The SolisAcura™ Probe Genotyping qPCR Mix is optimized for TaqMan®-style hydrolysis probes and powered by the SolisAcura™ Exo(+) DNA Polymerase with strong 5’→3’ exonuclease activity. It provides a high limit of detection, enhanced fluorescence, and reliable clustering even in up to 4-plex assays.
Ideal applications include:
Contact one of our account managers for more information, check out Solis BioDyne’s SolisAcura™ webinar or watch the short promotional video:
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