sbeadex Lightning: 11‑minute cell DNA purification

• Direct contact technical support
• Find products for your research

Purify high-quality genomic DNA from cultured cells in just 11 minutes with the new sbeadex Lightning Cell DNA Kit. Designed for rapid, simple, and safe DNA extraction, this kit streamlines your cell-based workflows—especially when screening many samples for gene editing QC or routine assay set‑up.

Built on superparamagnetic beads and an innovative binding chemistry, sbeadex Lightning binds and washes DNA simultaneously. A single water wash replaces hazardous ethanol or high-chaotropic washes, reducing hands‑on steps and minimizing exposure to harmful reagents. The result: clean, inhibitor‑free DNA ready for sensitive downstream applications, including qPCR and NGS.

Key performance highlights

• Fast and simple: 4‑step protocol including lysis; incubation time totals 11 minutes per sample, while retaining the advantages of proven magnetic bead workflows such as scalability and easy automation.
• Broad applicability: Works across a range of input amounts. For HEK293 cells, linear DNA yields were observed up to 5 × 10^5 cells, supporting varied sample loads without compromising output.
• High integrity DNA: Produces high‑molecular‑weight DNA suitable for applications that benefit from long fragments, such as long‑read sequencing and comprehensive genome interrogation.
• Clean DNA for downstream success: Efficient removal of impurities and inhibitors ensures reliable performance in qPCR and NGS.

Sustainability and efficiency
sbeadex Lightning reduces liquid waste, plastic consumption, and protocol time compared to market‑leading competitor kits tested on HEK293 cells. Per sample, the workflow cuts:

• Liquid waste to 0.82 mL (vs 1.6–3.36 mL),
• Plastic waste to 2 g (vs 3.1–4.76 g),
• Incubation time to 11 minutes (vs 13–41 minutes),
• Steps to 4 (vs 5–9).
  These reductions improve lab efficiency, lower waste‑disposal costs, and reduce environmental impact across shipping, storage, and instrumentation energy use.

Why it matters for your lab

• Speed: Accelerate iterative screens and scale up throughput with an 11‑minute incubation protocol.
• Safety and simplicity: One water wash, no ethanol or high‑salt washes.
• Quality: High‑molecular‑weight, inhibitor‑free DNA supports robust qPCR and NGS.
• Automation‑ready: Magnetic bead format translates seamlessly from single tubes to 96‑ and 384‑well platforms.