22 January 2026

Unlock bispecific antibody power with Bio X Cell

Bio X Cell now offers high-quality bispecific antibodies and custom engineering services to help you dissect immune pathways and translate cutting-edge bispecific concepts into in vivo research.


Precision meets power: bispecific antibodies from Bio X Cell

Bispecific antibodies are recombinant antibodies engineered to bind two distinct antigens simultaneously. By engaging two targets at once, they enable highly precise interrogation of immune pathways, signaling networks, and therapeutic mechanisms in preclinical models. For researchers working on next‑generation immunotherapies, bispecifics have become an essential tool to bridge the gap between concept and clinic.

Building on nearly 30 years of in vivo antibody expertise, Bio X Cell brings the same rigorous standards of purity, reproducibility, and in vivo readiness to every bispecific format. Each antibody is produced in an advanced facility, endotoxin‑tested (≤0.5 EU/mg), pathogen‑screened, and free from preservatives, stabilizers, and carrier proteins. This makes Bio X Cell bispecifics ideally suited for pharmacodynamic, efficacy, and mechanistic studies in humanized or syngeneic mouse models, where formulation consistency and low background are critical.

Through Bio-Connect, researchers in the BeNeLux can now easily access the full Bio X Cell bispecific offering:

Anti-mouse bispecific antibodies

These in vivo ready reagents are designed specifically for mouse models and closely replicate clinical constructs. They enable predictive mechanism of action and efficacy studies, including dual checkpoint blockade, immune cell redirection, and tumor microenvironment modeling.


Anti-human bispecific biosimilars

Bio X Cell’s anti‑human bispecific biosimilars mirror the structure and function of clinical therapeutics, providing robust tools for benchmarking and translational validation. This allows you to evaluate dosing strategies, combinations, and resistance mechanisms using constructs that reflect real‑world therapies.

Custom bispecific engineering

For projects that go beyond off‑the‑shelf solutions, Bio X Cell also offers custom bispecific engineering. From construct design and format selection to scalable production, their experts can help you rapidly progress from idea to in vivo‑ready antibody. Connect with your accountmanager to align construct design, timelines, and budgets to your specific project needs.

All bispecific antibodies are tested for purity, binding specificity, and dual‑target function, supporting diverse applications such as dual checkpoint inhibition, T‑cell or NK‑cell engagement, and fine‑tuning of immunomodulatory pathways. For additional scientific background on the promise and design of bispecifics, Bio X Cell recently contributed to an article in The Scientist, “Precision Meets Power: The Science Behind Bispecific Antibodies,” which provides an accessible overview of current concepts and technologies:

Researchers in the BeNeLux can rely on us for local support, logistics, and scientific guidance when implementing bispecific antibodies in new or existing projects. Whether you are exploring dual checkpoint combinations, engineering redirecting antibodies, or validating translational biosimilars, together with Bio X Cell we provide a robust, in vivo‑ready bispecific platform to help accelerate your research.

Would you like to explore the bispecific portfolio or discuss a custom project? Contact us at info@bio-connect.nl or connect with your account manager.

Unlock bispecific antibody power with Bio X Cell

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