Basic Pharma

USP and DSP (development) | rHSA | Yeast and Microbial Expression | GMP | ISO 13485 | Recombinant Proteins and Enzymes Manufacturing Services

Basic Pharma is a full-service provider located in the Netherlands that specializes in (bio)pharmaceutical product development, registration, manufacturing, and commercialization. The company focuses on developing and producing semi-solid formulations, such as creams, gels, and ointments, as well as liquid preparations, including nasal sprays, injectables, and syrups. Basic Pharma is a strategic partner to the pharmaceutical industry, academic institutions, and biotech start-ups, offering tailored services throughout the product lifecycle.

Recombinant Protein Production Services

In addition to these core pharmaceutical activities, Basic Pharma’s biotech department offers well-established infrastructure for recombinant protein production services and is progressing toward GMP compliance. The biotech department provides the infrastructure and expertise necessary to produce recombinant proteins for various applications, including:

  • Non-GMP production for preclinical research and industrial applications. Including R&D and process development.
  • Partnerships aimed at developing products for potential future GMP applications

Basic Pharma also offers a portfolio of high-quality recombinant proteins, each of which is rigorously tested to ensure consistent biological activity. Each batch is delivered with a Certificate of Analysis (CoA) that meets the stringent quality standards required for your research and development applications.

Recombinant Human Serum Albumin – rHSA

Recombinant Human Serum Albumin (rHSA) is a vital plasma protein that plays a key role in maintaining oncotic pressure and facilitating the transport of various endogenous and exogenous substances. Our recombinant rHSA is produced using Hansenula polymorpha yeast, offering a high-purity, animal-free alternative to traditional serum-derived HSA. It is ideal for applications requiring consistency, safety, and regulatory compliance.

Our rHSA is:

  • Produced in yeast (Hansenula polymorpha)
  • 100% animal-free
  • Highly consistent and scalable
  • Suitable for many applications, such as research, diagnostics, and cell culture media

Major product lines

  • Microbial (Yeast and bacteria) derived recombinant proteins
  • Recombinant Human Serum Albumin
  • Recombinant Histones
  • superfolder GFP (sfGFP)
  • TEV protease kit
  • Many more to come

Services

  • (Custom) recombinant protein production
  • Strain development support
  • USP and DSP (development)
  • Protein Analysis

All Products are for Research Use Only.

Custom services

Basic Pharma’s Biotech division offers comprehensive custom services for the development, expression, and purification of recombinant proteins, tailored to the needs of biotech, pharmaceutical, and academic partners. Their expertise focuses on microbial expression in yeast and bacteria, combining strain development, upstream processing, and downstream purification to deliver high-quality, animal-free proteins from lab to pilot scale using bioreactors of up to 50 L.

These services cover the full workflow from concept to purified protein, including support with expression construct design and strain optimization, fermentation in shake flasks and bioreactors, and multistep chromatographic purification. Additional services include filtration, buffer optimization, and optional lyophilization for long-term stability. Supported by in-house analytical capabilities such as HPLC and electrophoresis, Basic Pharma delivers proteins with high purity, consistent quality, and formats tailored to specific assay or formulation requirements.

Through Bio‑Connect, customers in the Benelux can access Basic Pharma’s custom recombinant protein production services with local scientific support. Our team helps define your project specifications, coordinates the custom workflows with Basic Pharma, and ensures efficient delivery of fit‑for‑purpose recombinant proteins tailored to your research or development applications.

More about Basic Pharma

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