EastMabBio manufactures high-quality recombinant proteins including interleukins, CSFs, TGFs plus others to support advanced therapy, with consistent lot-to-lot performance for research and clinical applications.
The rapid evolution of cell and gene therapy (CGT) has created an increasing demand for high-quality recombinant cytokines and growth factors that support robust cell expansion, differentiation, and functional activation.
With over 10 years of expertise in recombinant protein manufacturing, EastMabBio is a trusted manufacturer of GMP-grade recombinant cytokines, growth factors, extracellular matrix proteins, and cell culture supplements for advanced cell therapy applications. Designed for both research and clinical applications, EastMabBio’s recombinant proteins deliver high bioactivity, low endotoxin levels, excellent lot-to-lot consistency, and comprehensive regulatory documentation, helping accelerate the development of next-generation cell therapies.
Successful manufacturing of CAR-T, TCR-T, NK cell, stem cell, and iPSC-derived therapies relies on tightly controlled cell culture conditions. Recombinant proteins regulate critical biological processes, including:
Using high-quality recombinant proteins minimizes experimental variability while improving manufacturing reproducibility and scalability.
T cell-based immunotherapies, including CAR-T and TCR-T therapies, require precise cytokine supplementation to achieve optimal expansion and maintain therapeutic potency. Key recombinant proteins in this space include:
Interleukin-2 (IL-2) (Cat#Y02001N): The foundational cytokine for T cell proliferation and survival, essential for early-phase CAR-T expansion protocols.
Interleukin-7 (IL-7) (Cat#Y02401) & Interleukin-15 (IL-15) (Cat#Y02701): Critical homeostatic cytokines that promote memory T cell development and enhance long-term persistence in vivo.
Interleukin-21 (IL-21) (Cat#Y02901): A powerful modulator that boosts NK cell cytotoxicity and supports the generation of stem cell-like memory T cells.
EastMabBio recombinant cytokines are manufactured using advanced mammalian expression systems, ensuring proper protein folding, glycosylation, and bioactivity comparable to native human proteins.
Beyond T cell therapies, the expansion of induced pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) relies heavily on recombinant growth factors:
FGF-basic (bFGF): Maintains pluripotency in iPSC cultures, a cornerstone for scalable differentiation into therapeutic cell types.
EGF (Epidermal Growth Factor): Promotes proliferation of epithelial and neural progenitor cells.
TGF-beta family proteins: Guide lineage-specific differentiation critical for tissue engineering applications.
VEGF165 (Cat#Y04701): Supports endothelial specification and vascularization in tissue engineering applications.
Beyond its extensive portfolio of recombinant cytokines and growth factors, EastMabBio also provides integrated cell culture solutions to support advanced cell therapy and regenerative medicine research.
Their product offerings include:
To meet diverse research and manufacturing needs, EastMabBio also offers custom recombinant protein development and OEM/ODM manufacturing services, including customized protein expression, formulation optimization, quality testing, and scalable GMP production.
EastMabBio combines GMP-compliant manufacturing, ISO-certified quality systems, and comprehensive Regulatory Support Files (RSFs) to meet the evolving requirements of cell therapy and biopharmaceutical development.
To support supplier qualifications and regulatory submissions, they provide comprehensive Regulatory Support Files (RSFs), including:
Their complete documentation package helps customers streamline quality audits, regulatory submissions, and commercial manufacturing.
EastMabBio is a trusted manufacturer of recombinant proteins for advanced cell therapy and biopharmaceutical applications. Their portfolio includes 200+ recombinant proteins, spanning cytokines, growth factors, extracellular matrix proteins, serum replacement proteins, and culture supplements. Supported by GMP-compliant manufacturing, comprehensive RSFs, and scalable production capabilities, EastMabBio helps customers accelerate development from research to commercialization.
Whether you’re developing CAR-T, TCR-T, NK cell therapies, stem cell products, or regenerative medicine applications, EastMabBio delivers reliable GMP-grade recombinant proteins for advanced research and manufacturing workflows. These solutions are available in the Benelux through Bio-Connect, together with local support for product selection, pricing, custom services, and technical questions.
Please contact your Bio-Connect account manager or get in touch via our contact page to discuss the best solution for your project.
Recombinant Proteins | Cytokines | Growth Factors | Antibodies | RUO, GMP and ISO 13485 | Cell Culture Reagents | Cell Culture Proteins for Cell Therapy | Cell Culture Proteins for Cultivated Meat
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