Prolytix pooled platelet poor plasma (HPPP-0400) delivers consistency, low platelet counts, and verified coagulation performance for coagulation testing and assay development and validation.
As coagulation assays continue to evolve in complexity and sensitivity, laboratories require plasma sources that minimize biological variability while delivering reliable performance. Platelet poor plasma (PPP) plays a critical role in ensuring accurate clotting measurements, particularly in assays such as PT, aPTT, and fibrinogen testing.
Prolytix HPPP-0400 addresses these needs by offering a pooled normal plasma solution developed specifically for reproducibility and long term study support.
Pooled from 30 qualified donors, Prolytix HPPP-0400 provides a normalized coagulation profile that reduces donor to donor variability, an important advantage for laboratories performing validation studies or comparative testing.
The product is rigorously processed to achieve a platelet count of less than 10,000 platelets/µL, qualifying it as true platelet poor plasma. This low platelet content helps minimize platelet derived interference that can otherwise impact sensitive coagulation assays.
Each lot is verified to ensure:
This level of characterization supports confidence in both research and diagnostic applications.
Prolytix HPPP-0400 is supplied in 1 mL ready to use aliquots, allowing laboratories to reduce preparation time, avoid unnecessary freeze–thaw cycles, and limit sample waste. Custom aliquot sizes are also available to support automation platforms or specialized workflows.
The plasma is shipped frozen on dry ice and offers long term stability of up to five years when stored at –70 °C or colder, making it well suited for extended research programs and multi phase validation studies.
This platelet poor pooled plasma is ideal for a wide range of applications, including:
When data quality and reproducibility are critical, pooled platelet poor plasma provides a clear advantage. Prolytix HPPP-0400 delivers reduced biological variability, verified coagulation performance, lot to lot consistency, and a reliable supply for long term research. For laboratories who cannot afford uncertainty, Prolytix HPPP-0400 offers a solid foundation for confident coagulation testing.
Test Specifications:
| Test / Analysis | Specification |
| PT / APTT | Reported |
| Fibrinogen (Clauss Determination) | ≥ 200 mg/dL |
| Deficient Plasma Factor | < 1% |
| All Other Plasma Factors | 50 % ≤ factor % ≤ 150 % |
| Turbidity @ A320, A400, A530, A650 nm | Reported |
Test Results:
| Test / Assay | Test Results |
| PT | 12.8s |
| APTT | 36s |
| Fibrinogen (Clauss Determination) | 303 mg/dL |
| Factor II | 69% |
| Factor V | 87% |
| Factor VII | 89% |
| Factor VIII | 82% |
| Factor IX | 102% |
| Factor X | 75% |
| Factor XI | 73% |
| Factor XII | 63% |
All Prolytix products are available through our webshop. If you have any (technical) questions, please contact your account manager or our technical support team. We are happy to assist you.
Coagulation & Hematology | Protein (human & animal) | Inhibitors | Fluorogenic Substrates | Antibodies | Factor Defcient Plasmas | Clotting Factors | Collection Tubes
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