MSVA-741R – The Most Thoroughly Validated MTAP Antibody Now Available via Bio-Connect

• Direct contact technical support
• Find products for your research

Why Choose MSVA-741R?

• Extensive Validation on Normal Tissue: MSVA-741R has been validated on 76 different normal tissue types, following the stringent guidelines set by the International Working Group of Antibody Validation (IWGAV).
• Large-Scale Tumor Testing: In addition to normal tissue validation, this antibody was used to assess MTAP expression in 13,067 tumors across 149 distinct categories, providing crucial data on MTAP deficiency in a wide variety of cancers. [Gorbokon et al. Am J Surg Pathol. 2024.]
• Reliable Performance: MSVA-741R consistently delivers robust and reproducible results, establishing it as a reliable tool for immunohistochemistry (IHC).
• Key Research Applications: MTAP expression loss, which is usually caused by homozygous 9p21.3 deletion, plays a significant role in the development of many cancers. Detecting this is especially valuable for malignant mesothelioma, urothelial cancer, lung cancer, pancreatic adenocarcinoma and more.
• Open Access to Data: Extensive validation images and data are available in the Normal Tissue Gallery & Cancer Tissue Gallery on the MS Validated Antibodies website.

Supporting Your Research

MTAP expression loss occurs in up to 10% of all cancers, and MSVA-741R is a powerful tool for identifying these cases. It stands out for researchers seeking a robust and reliable antibody for their IHC studies.

Interested in learning more or want to request information? Order their products from our webshop. If you require more information about a product, please don’t hesitate to contact your account manager or our technical support team.