20 November 2019

NF-kB signaling pathway inhibitors

Inhibitors on NF-kB Signaling pathway from Selleck Chemicals are available at Bio-Connect Life Sciences


Nuclear factor kappa beta (NF-kB) signaling pathway consist of proteins that function as transcription factors that regulate expression of genes, and therefore influencing a broad range of biological processes including immune response, inflammation and cell proliferation. Stimuli such as cellularstress, cytokines, free radicals, UV radiation, oxidized LDL, and bacterial or viral antigens activates this pathway.

Activated NF-kB complexes are translocated to the nucleus where it binds to specific sequences of DNA called response elements to induce target gene expresion. Incorrect regulation of the NF-kB signaling pathway might lead to disease including cancer, inflammatory and autoimmune diseases, viral infections, improper immune development.

NF-kB pathway

NF-kB products

Panobinostat (LBH589) [404950-80-7] (S1030)
Vorinostat (SAHA, MK0683) [149647-78-9] (S1047)
Entinostat (MS-275) [209783-80-2] (S1053)
PCI-34051 [950762-95-5] (S2012)
TPCA-1 [507475-17-4] (S2824)
IMD 0354 [978-62-1] (S2864)
IKK-16 (IKK Inhibitor VII) [873225-46-8] (S2882)
Sodium 4-Aminosalicylate [6018-19-5] (S4073)
QNZ (EVP4593) [545380-34-5] (S4902)
RGFP966 [1396841-57-8] (S7229)
SC75741 [913822-46-5] (S7273)
JSH-23 [749886-87-1] (S7351)
Nexturastat A [1403783-31-2] (S7473)
Bardoxolone Methyl [218600-53-4] (S8078)
More Selleck Chemicals inhibitors and screening libraries can be found in our webshop

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