19 May 2022

New NF-light™ Serum ELISA

The NF-light™ Serum ELISA has made it easy for every lab to research neurodegenerative diseases by measuring NF-light values in serum.


IBL International (Tecan) proudly present the new NF-light™ Serum ELISA. The NF-light™ Serum ELISA is a Research Use Only assay for quantitative measurements of human Neurofilament light (NF-L) protein in serum samples. The kit is intended for professional use. The NF-light™ Serum ELISA can also be used for research on samples containing NF-L from rat, mouse, bovine or macaque sources as the antibodies in the assay recognizes NF-L from these species as well.

Catalog number:30210101
Regulatory status:RUO
Packing:12 x 8
Method:ELISA
Incubation time:1 x 2h, 1 x 90min, 1 x 30min, 1 x 15min.
Standard range:0.5 – 40 pg/mL
Specimen / volumes:100 µL serum
Substrate / isotope:TMB 450 nm
For concrete data please download the Instruction for Use.

For research use only. Not for use in diagnostic procedures.

Bio-Connect Diagnostics distributes the new NF-light™ Serum ELISA in the Benelux. If you have any questions, please contact the helpdesk.

Background

Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are important for the maintenance of the axonal caliber and morphological integrity, which affect the velocity and fidelity of neuronal transmissions. Three different neurofilament chains exist, named according to their size. These are Neurofilament light, medium and heavy respectively. The Neurofilament light constitutes the backbone to which the heavier chains co-assemble, forming the neurofilament fiber. Following injuries of nerve cells due to direct trauma or slow degenerative processes, the content of the cell is released into the surrounding compartment allowing quantitative determinations of the axonal proteins.

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