MCE Bioactive Compound Libraries
MedChem Express (MCE) One-Stop Compound Screening Platform supplies more than 200 screening libraries and a variety of compounds and phenotypic screening service.
Superior bioactivity, low endotoxin levels, high purity, excellent lot-to-lot consistency. Unlock New Possibilities with 12,000+ High-Quality Recombinant Proteins.
MCE provides a wide range of high-quality recombinant proteins, including cytokines, enzymes, growth factors, hormones, receptors, transcription factors, and antibody fragments. These proteins are crucial for cell growth, signaling, and differentiation, and are vital tools for studying protein structure and function, disease mechanisms, and drug targets.
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Over 12,000 recombinant protein products
MCE has always been dedicated to providing top-quality products. Through a stringent quality control system and robust quality assurance processes, MCE ensures that the recombinant proteins exhibit outstanding characteristics, exceptional purity, and optimal biological activity, all of which meet the highest standards.
The purity of MCE’s mouse IL-13Rα₂ exceeds 95%, as determined by SDS-PAGE under reducing conditions and HPLC analysis.
MCE’s human GM-CSF promotes the proliferation of TF-1 cells, with an ED₅₀ of less than 0.5 ng/mL.
The ED50 values of MCE’s human VEGF165 from three distinct lots are highly consistent.
A side-by-side comparison of the ED50 values shows that MCE’s human VEGF165 is more potent than that of a competitor brand.
Category | Product Name | |
MedChemExpress (MCE) provides a range of cytokines and growth factors, including interleukins, chemokines, interferons, transforming growth factors, fibroblast growth factors, as well as the cytokine receptor family. | IL-2 Protein | IFN-gamma Protein |
TGF beta 1 Protein | EGF Protein | |
Covering a series of immune checkpoint molecules, including PD-1/PD-L1, CTLA-4, TIM-3, OX40, TIGIT, and novel immune checkpoint proteins such as butyrophilins (BTNs). | PD-1 Protein | PD-L1 Protein |
CTLA-4 Protein | CD40 Protein | |
Covering popular targets, including BCMA, CD19, MSLN, HER2, MUC1, CD22, ROR1, and providing labeled target antigens, such as fluorescently labeled and biotin-labeled, to support CAR-T research and development. | BCMA/TNFRSF17 Protein | CD19 Protein |
EpCAM/TROP1 Protein | HER3 Protein | |
CD molecules function as cell adhesion molecules, cytokine receptors, ion channels, or nutrient transport proteins, playing various roles in immune system function. CD molecules are commonly used as cell markers for immune antigen recognition. | CD3 epsilon Protein | CD8 beta Protein |
B7-1/CD80 Protein | CD4 Protein | |
Receptor proteins include enzyme-linked receptors, cell adhesion molecules, G protein-coupled receptors, nuclear receptors, pattern recognition receptors, Notch, and other receptor families. | GLP1R Protein | TrkB Protein |
PVR/CD155 Protein | Siglec-15 Protein | |
The binding activity between the Fc fragment of antibodies and receptors affects the efficacy of antibody drugs. MedChemExpress (MCE) offers a range of high-quality recombinant Fc receptor proteins for antibody drug modification and evaluation, facilitating the development of antibody drugs. | FcRn Protein | Fc Receptor-like Proteins |
Fc-gamma Receptor Protein | Fc gamma RII/CD32 Proteins | |
Most biological processes in organisms are regulated by enzymes. MedChemExpress (MCE) provides a variety of enzyme-related proteins, including various families of enzymes and inhibitors, such as MMPs, proteases, CDKs, phosphatases, protease inhibitors, kinase inhibitors, and CDK inhibitors. | Cathepsin A Protein | ACE2 Protein |
MMP-9 Protein | Aminopeptidase N/APN Protein | |
MedChemExpress (MCE) has developed a series of high-quality recombinant proteins, including C3, C5, MASP, complement regulatory factors, etc., to support research on the complement system mechanism and related diseases. | Complement C3/C3a Protein | Complement C5/C5a Protein |
CFHR2 Protein | CFHR1 Protein | |
Ubiquitination regulates various cellular processes, including cell division and differentiation, responses to environmental stress, cell differentiation, immune reactions, DNA repair, and apoptosis. | UCHL1 Protein | USP14 Protein |
KEAP1 Protein | UBE2I Protein | |
MedChemExpress (MCE) has developed nearly a thousand recombinant biotinylated and Avi-Tag proteins, which can be used in protein purification, protein-protein interactions, detection, screening, and other research applications. | PCSK9 Protein (Biotinylated) | PD-L1 Protein (Biotinylated) |
Siglec-15 Protein (Biotinylated) | CD79B Protein (Biotinylated) | |
FITC-Labeled CD47 Protein | PE-Labeled Mesothelin Protein | |
FITC-Labeled HGFR Protein | FITC-Labeled CD99 Protein | |
MedChemExpress (MCE) provides a variety of recombinant viral proteins, including influenza viruses, coronaviruses, HIV, hepatitis viruses, and more, to support research on viral infections. | SARS-CoV S Protein | SARS-CoV-2 S Protein |
NA/Neuraminidase Protein | MERS-CoV Spike/S1 Protein | |
MedChemExpress (MCE) GMP recombinant proteins are manufactured under specific guidelines to ensure product quality and consistency. Each lot of our GMP-grade recombinant proteins undergoes rigorous QC testing tests. | GMP IL-4 Protein | GMP EGF Protein |
GMP FLT3LG Protein | GMP IL-18 Protein | |
Animal-free recombinant proteins have the same biological activity as proteins produced using standard laboratory techniques, while researchers do not have to worry at all about traces of animal components or mammalian pathogens affecting their experiments. | Animal-Free Beta-NGF Protein | Animal-Free IFN-beta Protein |
Animal-Free IGF2 Protein | Animal-Free IL-17A Protein |
Cited in: Adv Sci (Weinh). 2024 Jun 20:e2404171.
TNF-α (HY-P7058) treatment upregulates the expression of adhesion molecules on the surface of HUVECs. Additionally, by increasing the expression of CXCR4 and VLA-4, it enhances the inflammatory chemotaxis of MMCLs, greatly improving their transendothelial migration efficiency.
An organoid is a 3D multicellular in vitro tissue construct that mimics the complex structure and functionality of corresponding in vivo organ. MedChemExpress (MCE) provides a range of cytokines, small molecule inhibitors, basement membrane matrix, and various organoid culture kits
ICPs have been identified and studied in cancer, including PD-1, CTLA-4, LAG3 and TIGIT, etc. MedChemExpress (MCE) offers recombinant proteins, specific small molecule inhibitors/agonists, and antibody inhibitors for immune checkpoint research.
SARS-CoV is a positive-stranded RNA virus belonging to the family Coronaviridae. The SARS-COV-2 genome encodes at least sixteen non-structural proteins and four structural proteins.
Stem cells are able to differentiate into different types of cells in the body and have unique abilities to self-renew and recreate functional tissues. MedChemExpress (MCE) offers a range of products related to stem cell culture.
MMPs are widely involved in a variety of physiological and pathological processes, and plays an important role in cell migration, tissue remodeling, etc. MMPs have emerged as significant biomarkers and therapeutic targets in clinical diagnostics and treatment.
Immune cell culture models are essential tools in immunology research. MCE can provide a range of high-quality cytokines for the in vitro culture, activation, and differentiation of various immune cells, to enhance the controllability and reproducibility of immune cell cultures.
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