MedChem Express (MCE)

Inhibitors | Agonists | Recombinant Proteins | Dyes | Assay Kits | Compound Libraries | Drug Screening | PCR | Cell Culture Reagents | Custom Synthesis, Screening, ADC, PROTAC Solutions

Current MCE promotions

MedChem Express Recombinant Proteins Banner - Get a free sample

Contact us now to request your free sample. This promotion is valid until 31-12-2026.

Promotion Terms and Conditions

• The promotion cannot be applied retroactively.
• Standard shipping costs (€38,-) still apply.
• Bio-Connect reserves the right to modify, cancel, or withdraw this promotion at any time.


About MedChemExpress (MCE)

MedChemExpress is a leading global supplier in the life sciences research field, dedicated to empowering researchers with high-quality research chemicals and biological tools. The company serves a diverse customer base, including universities, research institutions, and pharmaceutical companies, offering an extensive product portfolio and professional services designed to accelerate discovery and advance scientific understanding.

Comprehensive product portfolio:

With decades of dedication to the industry, MedChemExpress boasts more than 200,000+ bioactive molecules, covering a wide range of signaling pathways and research areas including Target and Disease Mechanism Studies, Detection, Analysis, and Quality Control, Disease Modeling and Drug Screening, Stem Cell Research and Cell Therapy, Gene Therapy, and other drug discovery fields.

  • Target and Disease Mechanism Studies:Inhibitors & Agonists, PROTAC, ADC, Recombinant Protein, Inhibitory Antibodies, Peptides, Induced Disease Models Products, Animal Feed Products;
  • Detection, Analysis, and Quality Control:Isotope-Labeled Compounds, Fluorescent Dye, Reference Standards, Antibodies, Enzymes, Kits;
  • Stem Cell Research and Cell Therapy: GMP small molecules, Organoid-related proteins, Matrigel, Culture medium, Serum;
  • Gene Therapy: Small RNA, Liposomes, Adjuvants, Restriction Endonucleases, PCR, qPCR Kits.

One-Stop AI-based Compound Screening Platform

MedChemExpress One-Stop Compound Screening Platform supplies more than 200 screening libraries and a variety of compounds and phenotypic screening services. These services include DNA-encoded compound library screening, virtual screening, high-throughput screening (HTS), ion channel detection, kinase screening & profiling, phenotypic screening, affinity mass spectrometry screening, customized compound synthesis, structural optimization and analysis services, etc. Our commitment is to continuously advance our platform capabilities. By creating a one-stop drug discovery service for scientific research, we aim to unlock infinite possibilities for innovation.

Industry-Leading Bioinformatics

  • Targets and signaling pathways: JAK, STAT, PD-1/PD-L1, KRAS, STING, Ferroptosis, etc.
  • Authoritative support: In vivo/In vitro experimental protocols from the literature
  • Dynamic data: 150,000+ solubility measurements, tens of millions of genetic information entries, Clinical/approval tracking
  • Wide applications: Pharmacology and biological research, covering 400+ disease/field studies, including cancer, neurology, inflammation, metabolism, stem cells, etc.
  • 7×24 Professional Services: Having served over one million customers

Robust Multi-Level Quality Control

  • International Standards: Strict compliance with ISO 9001:2015, ISO 9001, ISO 17025, ICH Q7, quality and environmental management systems
  • Complete Platform: 400+ precision instruments, 1,000 R&D and analytical staff
  • Comprehensive Testing: NMR, HPLC, LC-MS, IR, Elemental analysis, etc.
  • Biovalidation Platform: Four Major Platforms (Molecular/Protein/Cell/In Vivo Experiments) Supporting Drug Efficacy Evaluation

Global Business and Warehousing Center

A global warehouse center covering North America, China, Europe, Japan, and other regions. With dozens of warehouses, they achieve next-day delivery in 90% of regions and quickly respond to global customer needs.

Top sellers

Publications

  • Nature. Published online December 2, 2021.

    Kagawa H, Javali A, Khoei HH, et al. Human blastoids model blastocyst development and implantation.

  • Cell. 2021;184(21):5375-5390.e16.

    Manford AG, Mena EL, Shih KY, et al. Structural basis and regulation of the reductive stress response.

  • Nature. 2021;596(7871):291-295.

    Monteys AM, Hundley AA, Ranum PT, et al. Regulated control of gene therapies by drug-induced splicing.

  • Cell. 2021;184(17):4579-4592.e24.

    Bosch B, DeJesus MA, Poulton NC, et al. Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.

  • Nature. 2021;594(7862):277-282.

    Pan Y, Hysinger JD, Barron T, et al. NF1 mutation drives neuronal activity-dependent initiation of optic glioma.

  • Cell. 2021;184(13):3528-3541.e12.

    Bi G, Su M, Li N, et al. The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling.

  • Nature. 2021;591(7850):477-481.

    Tigano M, Vargas DC, Tremblay-Belzile S, Fu Y, Sfeir A. Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance.

  • Cell. 2021;184(4):943-956.e18.

    Xiao P, Yan W, Gou L, et al. Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.

  • Science. 2021;371(6533):eabb2224.

    Yan R, Cao P, Song W, et al. A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.

  • Nature. 2021;590(7847):612-617.

    Lee JH, Kim JY, Noh S, et al. Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis.

Videos

MCE provides a one-stop solution for drug screening to accelerate early drug discovery!

Custom services

MedChemExpress (MCE) offers an extensive portfolio of custom services designed to support drug discovery and mechanism-of-action studies. Their capabilities include custom peptide synthesis at flexible scales with multiple purity levels and modification options, as well as recombinant protein expression services for high-quality research- and GMP-grade proteins.

Beyond biologics, MCE provides custom small-molecule synthesis tailored to specific targets or chemical series, enabling rapid access to novel analogues, tool compounds, and reference standards. Leveraging strong expertise in conjugation chemistry, MCE also supports ADC- and PROTAC-related custom projects, including the design and synthesis of payloads, linkers, and conjugates to accelerate targeted therapy and targeted protein degradation research.

Through Bio-Connect, customers can access MCE’s custom services with local scientific support. Our team helps define the right service strategy for your project and coordinates the collaboration with MCE to ensure efficient delivery of high-quality, project-specific solutions.

More about MedChem Express (MCE)

Sign up for our research newsletter

We gladly support you by keeping you updated on our latest products and developments


Need help? Contact our technical support
Contact