24 March 2021

InVivoSIM™ biosimilar antibodies

Discover Bio X Cell InVivoSIM™ research-grade biosimilar antibodies suitable for functional assays, in vivo applications, and more.


Bio X Cell InVivoSIM™ research-grade biosimilar monoclonal antibodies have the same active biological components as the original therapeutic antibodies. Biosimilars make it possible to study the biological effects of a drug without the need to source an expensive pharmaceutical-grade therapeutic. They can be used in functional assays, pharmacokinetic assays, ELISA, IHC, WB, flow cytometry, and in in vivo applications including drug efficacy studies in humanized mouse models. The InVivoSIM™ biosimilar antibodies feature greater than 95% purity and are free of preservatives, stabilizers, and carrier proteins. They are screened for murine pathogens and protein aggregation, feature binding validation via Immunoblot and are guaranteed to contain less than 1 endotoxin unit per milligram.

InVivoSIM™ biosimilar antibodies feature

  • Exceptional purity: each lot is QC tested for purity using SDS-PAGE and are preservative, stabilizer, and carrier protein-free.
  • Binding validation: each lot of InVivoSIM™ product is validated for antigen binding by immunoblot.
  • Ultra-low endotoxin levels: the level of endotoxin is QC tested for each lot. The InVivoSIM™ products are ≤ 1EU/mg. If endotoxin levels below 1EU/mg are required, please contact technical support to discuss your needs.
  • Pathogen free: each lot of InVivoSIM™ product is screened for an exhaustive panel of murine pathogens. The results are detailed on product-specific datasheets, to help you adhere to IACUC and animal facility requirements.
  • Low protein aggregation: each lot of InVivoSIM™ product is QC tested for aggregate level and guaranteed to be below 5% of the total protein.

InVivoSIM™ antibodies are for Research Use Only (RUO) and not for therapeutic use.

All InVivoSIM antibodies

InVivoSIM Anti-Human TNFα (Adalimumab Biosimilar) (SIM0001)
InVivoSIM Anti-Human EGFR (Cetuximab Biosimilar) (SIM0002)
InVivoSIM Anti-Human PD-1 (Nivolumab Biosimilar) (SIM0003)
InVivoSIM Anti-Human CTLA-4 (Ipilimumab Biosimilar) (SIM0004)
InVivoSIM Anti-Human HER2 (Trastuzumab Biosimilar) (SIM0005)
InVivoSIM Anti-Human TNFα (Infliximab Biosimilar) (SIM0006)
InVivoSIM Anti-Human VEGF (Bevacizumab Biosimilar) (SIM0007)
InVivoSIM Anti-Human CD20 (Rituximab Biosimilar) (SIM0008)
InVivoSIM Anti-Human PD-L1 (Atezolizumab Biosimilar) (SIM0009)

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