14 May 2024

Mouse Immune Cell Depletion Antibodies For in vivo Use

Bio X Cell offers monoclonal antibodies for invivo cell-specific depletion studies. These antibodies contribute to understanding the role of specific cell types in immunological processes and diseases. Explore their catalog.

Bio X Cell offers a range of monoclonal antibodies to mouse cell surface proteins for in vivo cell specific depletion studies. in vivo cell specific depletion experiments are widely used to establish the role of a specific cell type in a variety of immunological processes and diseases.

These antibodies are reported for use in in vivo studies where the injected depletion antibody is intended to deplete a specific cell type. These types of experiments are useful to extend and confirm results obtained with genetic knock-out mouse strains or to provide information about the direct biological relevance of a certain cell type.

These antibodies mediate cell depletion through multiple mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and antibody-dependent cellular phagocytosis (ADCP). For information about the dosage and kinetics of administration for the in vivo injection of these antibodies, we have compiled an up-to-date list of references for each depletion antibody. These can be found on the individual product pages. We encourage you to review these papers and others in the literature to find the optimal protocol for your experimental system and goals. Take a look at the table on Bio x Cell’s deplation page.

Featured Cell Depletion Antibodies

InVivoMAb anti-mouse B220 (BE0067)
InVivoMAb anti-mouse CD19 (BE0150)
InVivoPlus anti-mouse CD20 (BP0356)
InVivoPlus anti-mouse CD3epsilon (BP0001-1)
InVivoMAb anti-mouse Thy1.1 (CD90.1) (BE0214)
InVivoMAb anti-mouse Thy1 (CD90) (BE0076)
InVivoMAb anti-mouse TCRbeta (BE0102)
InVivoPlus anti-mouse CD4 (BP0003-1)
InVivoMAb anti-mouse CD4 (BE0119)
InVivoPlus anti-mouse CD8alpha (BP0061)
InVivoPlus anti-mouse CD8alpha (BP0004-1)
InVivoPlus anti-mouse CD8alpha (BP0117)
InVivoMAb anti-mouse CD8 (Lyt 2.1) (BE0118)
InVivoMAb anti-mouse CD8beta (Lyt 3.2) (BE0223)
InVivoPlus anti-mouse CD25 (IL-2Ralpha) (BP0012)
InVivoMAb anti-mouse Vgamma2 TCR (BE0168)
InVivoPlus anti-mouse Thy1.2 (CD90.2) (BP0066)
InVivoPlus anti-mouse NK1.1 (BP0036)
InVivoMAb anti-mouse CD122 (IL-2Rbeta) (BE0298)
InVivoPlus anti-mouse Ly6G (BP0075-1)
InVivoMAb anti-mouse Ly6G/Ly6C (BE0320)
InVivoMAb anti-mouse/human IL-5 (BE0198) 
InVivoMAb anti-mouse CCR3 (CD193) (BE0316)
InVivoPlus anti-mouse Ly6G/Ly6C (Gr-1) (BP0075)
InVivoPlus anti-mouse CSF1R (CD115) (BP0213)
InVivoMAb anti-mouse F4/80 (BE0206) 
InVivoMAb anti-mouse CD317 (BST2, PDCA-1) (BE0311)
InVivoMAb anti-mouse c-Kit (CD117) (BE0293)
InVivoMAb anti-mouse CD3ε F(ab’)2 fragment (BE0001-1FAB)
InVivoMAb anti-mouse Ly6C (BE0203)

Mouse Immune Cell Depletion Antibodies For in vivo Use

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