Specialized in the synthesis of fluorescent substances

Chemodex is a Swiss company manufacturing an attractive product portfolio at very competitive prices. Chemodex is an expert in the synthesis of fluorescent substances derived from fluorophores such as coumarin, fluorescein, rhodamine and pyrene. The reagents are used as probes, stains, markers, NIR-labels, pH-sensors, ion indicators, chelators and in other applications (e.g. analytical biochemistry, immunoassays and microscopy) by life science researchers in academia, biotechnology and the diagnostics & pharmaceutical industry.

Chemodex is a part of AdipoGen Life Sciences, who also cooperates with a number of other manufacturers such as: Ancell CorporationBioVioticaChimerigen LaboratoriesInnaxonJaICA and South Bay Bio.

Bio-Connect supplies all their reagents in the Benelux. If you have any questions, please contact the helpdesk.

Major product lines from Chemodex

  • Common and new fluorescent probes
  • Stains/labels/dyes
  • Markers & probes
  • Metabolites
  • Building blocks & small molecules

DAF Compounds – Fluorescent probes for the detection of nitric oxide

Nitric oxide (NO) is involved in various physiological and pathological processes in the cell and has been implicated in vasodilation, neurotransmission, cytotoxicity, immune response and inflammation. Within cells, nitric oxide synthase (NOS) catalyses the conversion of arginine to citrulline and NO in the presence of molecular oxygen, tetrahydrobiopterin, NADPH and flavin cofactors. Due to the importance of NO, real time detection and quantification of NO is of great interest. However, the extremely short half-life of NO limits the study of its physiological effect in vivo. Therefore NO-sensitive fluorescent probes, such as DAF-2 have been designed and used in real-time imaging of NO.

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