Antibodies
Bio-Connect offers one of the most comprehensive portfolios of antibodies worldwide.
Innovative and high quality products focusing on advanced inflammation, immune response & immunometabolic research
AdipoGen Life Sciences, Inc. is a well-established manufacturer and worldwide distributor of innovative and high quality products focusing on advanced inflammation, immune response & immunometabolic research. Production is located in Switzerland, the US and Germany. A motivated team of highly-skilled individuals develops and manufactures new products for the life science research market.
They focus their efforts on inflammation and immune response, including inflammasomes, innate immunity, B- and T-cells immune regulation, neuroinflammation, obesity and immuno-oncology. AdipoGen Life Sciences owns chemical laboratories, enabling the company to isolate unique natural products, to develop new and innovative small molecules, and to manufacture rare antibiotics.
AdipoGen Life Sciences cooperates with a number of manufacturers such as: Ancell Corporation, BioViotica, Chemodex, Chimerigen Laboratories, Innaxon, JaICA and South Bay Bio.
Bio-Connect Life Sciences supplies all their products in the Benelux. If you have any questions, please contact the helpdesk.
MultimericCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations. MultimericCD40L™ has shown to suppress alum-induced IL-1β release and caspase-1 activation in a dose-, CD40- and time dependent manner, without affecting BMDM viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators. The secretion of caspase-1 independent inflammatory mediators has been shown to be unaltered or even enhanced.
Figure: CD40L (human) (multimeric) (rec.) (AG-40B-0010) does not need an enhancer to induce B cell activation.
lnVivoKines™ are a new generation of recombinant fusion proteins for immunotherapeutic, preclinical and translational in vivo research, developed in-house by AdipoGen Life Sciences. lnVivoKines™ are Fc-based fusion proteins using the Knobs-into-Holes (KlH) technology. Read more
Assays
Antibodies
Antibodies
Antibodies
Antibodies
Antibodies
Antibodies
Proteins / Signaling Molecules
Proteins / Signaling Molecules
Proteins / Signaling Molecules
Proteins / Signaling Molecules
Proteins / Signaling Molecules
Proteins / Signaling Molecules
Inflammasomes Proteins with Enhanced Activity Non-Animal Source Antibodies 
ELISA Kits pdf InVivoKines™ Functional Antibodies | Focus: Recombinant Antibodies pdf Rare Antibiotics & Unique Natural Products pdf GLP-1, GIP & GCG in Obesity and Diabetes Research B-Xpander™ - Unleash the Power of B Cell Expansion Progranulin [PGRN] - Marker of Neuroinflammation Obesity & Metabolism pdfHaselmayer P, Vigolo M, Nys J, Schneider P, Hess H. A mouse model of systemic lupus erythematosus responds better to soluble TACI than to soluble BAFFR, correlating with depletion of plasma cells.
Kowalczyk-Quintas C, Schuepbach-Mallepell S, Vigolo M, et al. Antibodies that block or activate mouse b cell activating factor of the tumor necrosis factor (Tnf) family (Baff), respectively, induce b cell depletion or b cell hyperplasia.
Eslami M, Meinl E, Eibel H, et al. Baff 60-mer, and differential baff 60-mer dissociating activities in human serum, cord blood and cerebrospinal fluid.
Kume M, Kiyohara E, Matsumura Y, et al. Ganglioside gd3 may suppress the functional activities of benign skin t cells in cutaneous t-cell lymphoma.
Singh K, Kadesjö E, Lindroos J, et al. Interleukin-35 administration counteracts established murine type 1 diabetes–possible involvement of regulatory T cells.
Ellisdon AM, Nold-Petry CA, D’Andrea L, et al. Homodimerization attenuates the anti-inflammatory activity of interleukin-37.
Ising C, Venegas C, Zhang S, et al. NLRP3 inflammasome activation drives tau pathology.
Müller K, Girl P, von Buttlar H, Dobler G, Wölfel R. Comparison of two commercial surrogate ELISAs to detect a neutralising antibody response to SARS-CoV-2.
Zheng M, Karki R, Vogel P, Kanneganti T-D. Caspase-6 is a key regulator of innate immunity, inflammasome activation, and host defense.
Sellami L, Rucheton B, Ben Younes I, et al. Plasma progranulin levels for frontotemporal dementia in clinical practice: a 10-year French experience.
Schneider KS, Groß CJ, Dreier RF, et al. The inflammasome drives gsdmd-independent secondary pyroptosis and il-1 release in the absence of caspase-1 protease activity.
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